Article
Enterovirus RNA in serum is a risk factor for beta-cell autoimmunity and clinical type 1 diabetes: a prospective study. Childhood Diabetes in Finland (DiMe) Study Group.
Journal of medical virology - 1 Jun 2000
Lönnrot M, Salminen K, Knip M, Savola K, Kulmala P, Leinikki P, Hyypiä T, Akerblom H K, Hyöty H
Abstract excerpt
Recent prospective studies have documented serologically an increased frequency of enterovirus infections in prediabetic children, indicating that these infections may initiate and accelerate the beta-cell damaging process several years before the clinical manifestation of type 1 diabetes. The aim of the present study was to establish whether these serological findings would be supported by the detection of...
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