Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biochemical Targets of the Isoflavone Genistein in Tumor Cell Lines

1 Jan 1995

Abstract excerpt

Dietary intake of soy is associated with a decreased risk of both hormone-dependent and hormone-independent cancers. It has been proposed that genistein, the predominant isoflavone in soy foods, is responsible for this effect. In this review, the potential mechanisms of action of genistein at the cellular level are critically examined to determine which are physiologically relevant. We concluded that (i) only...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet, Metabolism, and Disease
Share to Phytoestrogen effects and research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7892283
DOI: 10.3181/00379727-208-43840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biochemical Targets of the Isoflavone Genistein in Tumor Cell LinesPMID 7892283Read ↗

Effect of Genistein on In Vitro and In Vivo Models of CancerSemantic proximity Read ↗

Isoflavones and the prevention of breast and prostate cancer: new perspectives opened by nutrigenomicsSemantic proximity Read ↗

Genistein as a regulator of signaling pathways and microRNAs in different types of cancersSemantic proximity Read ↗

Antileukemic Activity of Genistein, a Major Isoflavone Present in Soy ProductsSemantic proximity Read ↗

Mechanisms underlying the dualistic mode of action of major soy isoflavones in relation to cell proliferation and cancer risksSemantic proximity Read ↗

Using DNA microarray analyses to elucidate the effects of genistein in androgen‐responsive prostate cancer cells: Identification of novel targetsSemantic proximity Read ↗

Genistein: A promising phytoconstituent with reference to its bioactivitiesSemantic proximity Read ↗

The role of early life genistein exposures in modifying breast cancer risk.Semantic proximity Read ↗

Gene Expression Profiling of Breast Cancer Cell Lines in Response to Soy Isoflavones Using a Pangenomic Microarray ApproachSemantic proximity Read ↗

Mechanism of action of genistein on breast cancer and differential effects of different age stagesSemantic proximity Read ↗

Genistein inhibits Brca1 mutant tumor growth through activation of DNA damage checkpoints, cell cycle arrest, and mitotic catastrophe.Semantic proximity Read ↗

Inhibition of cancer cell invasion and metastasis by genisteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.