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Article

Mode of Ezrin-Membrane Interaction as a Function of PIP2 Binding and Pseudophosphorylation.

Biophysical journal - 21 Jun 2016

Shabardina Victoria, Kramer Corinna, Gerdes Benjamin, Braunger Julia, Cordes Andrea, Schäfer Jonas, Mey Ingo, Grill David, Gerke Volker, Steinem Claudia

Abstract excerpt

Ezrin, a protein of the ezrin, radixin, moesin (ERM) family, provides a regulated linkage between the plasma membrane and the cytoskeleton. The hallmark of this linkage is the activation of ezrin by phosphatidylinositol-4,5-bisphosphate (PIP2) binding and a threonine phosphorylation at position 567. To analyze the influence of these activating factors on the organization of ezrin on lipid membranes and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27332129
DOI: 10.1016/j.bpj.2016.05.009
PMCID: PMC4919509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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