Article
Biomarker modulation in a nonhuman rhesus primate model for ovarian cancer chemoprevention.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2001
Brewer M, Utzinger U, Satterfield W, Hill L, Gershenson D, Bast R, Wharton J T, Richards-Kortum R, Follen M
Abstract excerpt
OBJECTIVE: The objective of this study was to explore whether a nonhuman primate model could be developed to test drugs for the prevention of ovarian cancer. METHODS: Nineteen adult female Rhesus macaques were given fenretinide (4HPR), oral contraceptives (OCP), the combination (4HPR + OCP), or n...
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