Article
Fenretinide (4-HPR): a preventive chance for women at genetic and familial risk?
Journal of biomedicine & biotechnology - 1 Jan 2012
Cazzaniga Massimiliano, Varricchio Clara, Montefrancesco Chiara, Feroce Irene, Guerrieri-Gonzaga Aliana
Abstract excerpt
The incidence and mortality of breast cancer have been recently influenced by several new therapeutic strategies. In particular our knowledge on cancer precursors, risk biomarkers, and genetics has considerably increased, and prevention strategies are being successfully explored. Since their discovery, retinoids, the natural and synthetic derivatives of vitamin A, have been known to play a crucial role in cell...
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