Human leukocyte antigen genes may outweigh racial background when generating a specific immune response in sarcoidosis.

doi:10.1183/09031936.01.17510460

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Article

Human leukocyte antigen genes may outweigh racial background when generating a specific immune response in sarcoidosis.

The European respiratory journal - 1 May 2001

Grunewald J, Eklund A

Abstract excerpt

Presented is a sarcoidosis patient of African origin, who was adopted at an early age and grew up in Sweden. This patient displayed an immune response identical to that previously reported in human leukocyte antigen (HLA)-DR17 positive Caucasian sarcoidosis patients in Scandinavia, with T-cell receptor AV2S3+ T-cells accumulating in the lungs. HLA typing also established that she was DR17 positive, which is a...

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