Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The polymorphism at codon 54 of the FABP2 gene increases fat absorption in human intestinal explants.

The Journal of biological chemistry - 26 Oct 2001

Levy E, Ménard D, Delvin E, Stan S, Mitchell G, Lambert M, Ziv E, Feoli-Fonseca J C, Seidman E

Abstract excerpt

Based on titration microcalorimetry and Caco-2 cell line transfection studies, it has been suggested that the A54T of the FABP2 gene plays a significant role in the assimilation of dietary fatty acids. However, reports were divergent with regard to the in vivo interaction between this polymorphism and postprandial lipemia. We therefore determined the influence of this intestinal fatty acid-binding protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Absorption
Share to Apolipoprotein A-I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fatty Acid-Binding Protein 7

Share to Fatty Acid-Binding Proteins

Share to Jejunum

Share to Microvilli

Share to Oleic Acid

Share to Organ Culture Techniques

Source

Identifiers

PMID: 11487582
DOI: 10.1074/jbc.M105713200

Genes

FABP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The polymorphism at codon 54 of the FABP2 gene increases fat absorption in human intestinal explants.PMID 11487582Read ↗

An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance.Semantic proximity Read ↗

A review of intestinal fatty acid binding protein gene variation and the plasma lipoprotein response to dietary components.Semantic proximity Read ↗

[Fatty acid binding protein 2 (FABP-2) polymorphism, obesity and insulin resistance].Semantic proximity Read ↗

Postprandial lipemia in subjects with the threonine 54 variant of the fatty acid-binding protein 2 gene is dependent on the type of fat ingested.Semantic proximity Read ↗

Association of the A/T54 polymorphism in the intestinal fatty acid binding protein with variations in plasma lipids in the Framingham Offspring Study.Semantic proximity Read ↗

The Ala54Thr Polymorphism of the Fatty Acid Binding Protein 2 Gene Modulates HDL Cholesterol in Mexican-Americans with Type 2 Diabetes.Semantic proximity Read ↗

Postprandial responses of individual fatty acids in subjects homozygous for the threonine- or alanine-encoding allele in codon 54 of the intestinal fatty acid binding protein 2 gene.Semantic proximity Read ↗

The A54T polymorphism of fatty acid-binding protein 2 may entail a reduction in fat-stimulated secretion of GIP that potentiates the adverse impact of fatty diets on insulin sensitivity.Semantic proximity Read ↗

Ala54Thr polymorphism of the fatty acid binding protein 2 gene and saturated fat intake in relation to lipid levels and insulin resistance: the Coronary Artery Risk Development in Young Adults (CARDIA) study.Semantic proximity Read ↗

Functional polymorphisms to modulate luminal lipid exposure and risk of colorectal cancer.Semantic proximity Read ↗

Variation in the FABP2 promoter affects gene expression: implications for prior association studies.Semantic proximity Read ↗

Threonine allele in codon 54 of the fatty acid binding protein 2 gene does not modify the fatty acid composition of serum lipids in obese subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.