Article
Variation in the FABP2 promoter affects gene expression: implications for prior association studies.
Diabetologia - 1 Feb 2004
Formanack M L, Baier L J
Abstract excerpt
AIMS/HYPOTHESIS: An Ala54Thr polymorphism in the FABP2 gene has previously been associated with insulin resistance and lipid oxidation rates in Pima Indians. Ala54Thr functionally alters the protein's ability to bind and transport dietary fatty acids. In the current report, we sought additional functional variation in FABP2 by sequencing putative regulatory regions. METHODS: More than 1.2 Kb of the putative...
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