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Article

Functional polymorphisms to modulate luminal lipid exposure and risk of colorectal cancer.

Cancer epidemiology - 1 Jun 2010

Kato Ikuko, Land Susan, Majumdar Adhip P, Barnholtz-Sloan Jill, Severson Richard K

Abstract excerpt

PURPOSE: Fat absorption may play a crucial role in colorectal carcinogenesis by determining intra-colonic exposure to potentially carcinogenic lipid metabolites. METHODS: We conducted a population-based case-control study that included 1163 cases and 1501 controls to examine whether individuals who carry genetic variants associated with lower lipid absorption have a higher risk of colorectal cancer. Using Taqman...

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Source

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Identifiers

PMID: 20308031
DOI: 10.1016/j.canep.2010.02.010
PMCID: PMC2905870

Genes

FABP2
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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