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cDNA microarray reveals altered cytoskeletal gene expression in space‐flown leukemic T lymphocytes (Jurkat)

18 Jun 2001

Abstract excerpt

ABSTRACT Cytoskeletal disruption and growth arrest consistently occur in space‐flown human acute leukemic T cells (Jurkat). Although the microtubules appear to reorganize during spaceflight, cells remain nonproliferative. To test the hypothesis that spaceflight alters cytoskeletal gene expression and may thus affect cytoskeletal function, we flew Jurkat cells on Space Transportation System (STS) 95 and compared...

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PMID: 11481229
DOI: 10.1096/fj.00-0820fje

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