Article
Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene.
Cytogenetics and cell genetics - 1 Jan 2001
Cook S A, Akeson E C, Calvano C, Johnson K R, Mandell J, Hawes N L, Bronson R T, Roderick T H, Davisson M T
Abstract excerpt
The paracentric inversion In(3)55Rk on mouse Chromosome 3 (Chr 3) was induced by cesium irradiation. Genetic crosses indicate the proximal breakpoint cosegregates with D3Mit324 and D3Mit92; the distal breakpoint cosegregates with D3Mit127, D3Mit160, and D3Mit200. Giemsa-banded chromosomes show the inversion spans approximately 80% of Chr 3. The proximal breakpoint occurs within band 3A2, not 3B as reported...
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