Article
Glutathione S-transferase T1-null genotype interacts synergistically with heavy smoking on lung cancer risk.
Environmental and molecular mutagenesis - 1 Jan 2001
Hou S M, Fält S, Nyberg F
Abstract excerpt
We studied the influence of genotype for glutathione S-transferase T1 (GSTT1) on susceptibility to lung cancer among 184 Swedish lung cancer patients (88 never-smokers and 96 ever-smokers) and 162 matched population controls (79 never-smokers and 83 ever-smokers), with special emphasis on gene-environment interactions. Cases had significantly lower frequency of the GSTT1-null genotype than that of controls among...
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