Article
P53 codon 72 genotypes in colon cancer. Association with human papillomavirus infection.
Research communications in molecular pathology and pharmacology - 1 Jul 2001
Sayhan N, Yazici H, Budak M, Bitisik O, Dalay N
Abstract excerpt
It has been reported that the p53Arg homozygous genotype could be a potential genetic risk factor for cancer. In this study we investigated the proportion of p53 codon 72 genotypes in patients with colon cancer and compared to a control population. A region of the p53 gene containing the polymorphic site was amplified by PCR and the genotypes were determined by restriction enzyme digestion. No significant...
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