Article
The recX gene potentiates homologous recombination in Neisseria gonorrhoeae.
Molecular microbiology - 1 Jun 2001
Stohl E A, Seifert H S
Abstract excerpt
In the pathogen Neisseria gonorrhoeae (Gc), the RecA protein is necessary for DNA repair, DNA transformation and pilus antigenic variation. Many bacteria contain a gene, recX, which has been suggested to downregulate recA through an unknown mechanism. To investigate the possible role of recX in Gc, we cloned and insertionally inactivated the recX gene. The recX loss-of-function mutant showed decreases in pilus...
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