Article
Role of UGT1A1 mutation in fasting hyperbilirubinemia.
Journal of gastroenterology and hepatology - 1 Jun 2001
Ishihara T, Kaito M, Takeuchi K, Gabazza E C, Tanaka Y, Higuchi K, Ikoma J, Watanabe S, Sato H, Adachi Y
Abstract excerpt
BACKGROUND AND AIM: Low-grade fasting hyperbilirubinemia is a common observation in healthy subjects (HS), whereas high-grade fasting hyperbilirubinemia is believed to be a characteristic finding of Gilbert's syndrome. This study was undertaken to assess the role of mutation in bilirubin UDP- glycosyltransferase gene (UGT1A1) on fasting hyperbilirubinemia. METHODS: Analysis of UGT1A1 and a caloric restriction...
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