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Article

Cloning of the ovine estrogen receptor-alpha promoter and functional regulation by ovine interferon-tau.

Endocrinology - 1 Jul 2001

Fleming J A, Choi Y, Johnson G A, Spencer T E, Bazer F W

Abstract excerpt

Interferon-tau (IFNtau), the ruminant pregnancy recognition signal, inhibits transcription of the estrogen receptor alpha (ERalpha) gene in the endometrial lumenal epithelium of the sheep uterus, thereby abrogating production of luteolytic PGF(2alpha) pulses. The effects of IFNtau are mediated in part by IFN-stimulated response elements (ISREs) and IFN regulatory factor elements (IRFEs). The promoter/enhancer...

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Identifiers

PMID: 11416007
DOI: 10.1210/endo.142.7.8245

Genes

PGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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