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Chronicling the discovery of interferon tau

26 Jul 2017

Abstract excerpt

It has been 38 years since a protein, now known as interferon tau (IFNT), was discovered in ovine conceptus-conditioned culture medium. After 1979, purification and testing of native IFNT revealed its unique antiluteolyic activity to prevent the regression of corpora lutea on ovaries of nonpregnant ewes. Antiviral, antiproliferative and immunomodulatory properties of native and recombinant IFNT were demonstrated...

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PMID: 28747540
DOI: 10.1530/rep-17-0257

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