Article
Pre-termination in aflR of Aspergillus sojae inhibits aflatoxin biosynthesis.
Applied microbiology and biotechnology - 1 May 2001
Matsushima K, Chang P K, Yu J, Abe K, Bhatnagar D, Cleveland T E
Abstract excerpt
The aflR gene product is the main transcriptional regulator of aflatoxin biosynthesis in Aspergillus parasiticus and Aspergillus flavus. Although A. sojae strains do not produce aflatoxins, they do have an aflR homologue. When compared with the aflR of A. parasiticus, the A. sojae gene contains two mutations: an HAHA motif and a premature stop codon. To investigate the functionality of the A. sojae aflR gene...
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