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Article

Adenovirus type 7 induces interleukin-8 production via activation of extracellular regulated kinase 1/2.

Journal of virology - 1 Jul 2001

Alcorn M J, Booth J L, Coggeshall K M, Metcalf J P

Abstract excerpt

Infection with adenovirus serotype 7 (Ad7) frequently causes lower respiratory pneumonia and is associated with severe lung inflammation and neutrophil infiltration. Earlier studies indicated release of proinflammatory cytokines, specifically interleukin-8 (IL-8), by pulmonary epithelial cells following infection by Ad7. However, the mechanism of IL-8 induction by Ad7 is unclear. We have explored the role of the...

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Identifiers

PMID: 11413312
DOI: 10.1128/JVI.75.14.6450-6459.2001
PMCID: PMC114368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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