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Enhancement human cytomegalovirus replication in a human lung fibroblast cell line by interleukin-8

1 Nov 1994

Abstract excerpt

We examined the effects of interleukin-8 (IL-8) on cytomegalovirus (CMV) replication in human fibroblasts. Exposure of fibroblasts to IL-8 augmented both infectious virus production and replication of CMV, with concomitant increases in the levels of both the transcript of the CMV pp71 genome and the synthesis of the CMV late antigen. We also found that CMV selectively induced transcripts of the IL-8 type 1...

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Share to Cytomegalovirus and herpesvirus research
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Identifiers

PMID: 7933146
DOI: 10.1128/jvi.68.11.7582-7585.1994

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