Article
Recent biologic and genetic advances in neuroblastoma: Implications for diagnostic, risk stratification, and treatment strategies.
Seminars in pediatric surgery - 1 Oct 2016
Newman Erika A, Nuchtern Jed G
Abstract excerpt
Neuroblastoma is an embryonic cancer of neural crest cell lineage, accounting for up to 10% of all pediatric cancer. The clinical course is heterogeneous ranging from spontaneous regression in neonates to life-threatening metastatic disease in older children. Much of this clinical variance is thought to result from distinct pathologic characteristics that predict patient outcomes. Consequently, many research...
Topics
- Child
- Child, Preschool
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Infant
- Infant, Newborn
- Neoplasm Staging
- Neuroblastoma
- Prognosis
- Risk Assessment