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Article

Molecular determination of X inactivation pattern correlates with phenotype in women with a structurally abnormal X chromosome.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000

Wolff D J, Schwartz S, Carrel L

Abstract excerpt

PURPOSE: To correlate the X inactivation pattern, as determined by one or more molecular assays, with phenotype in individuals with structurally abnormal X chromosomes. METHODS: We utilized methylation analysis of androgen receptor (AR) and Fragile X (FMR1) genes and expression studies of an XIST polymorphism to assess X inactivation patterns of 28 females with structurally abnormal X chromosomes. Individuals...

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Share to Chromosomes, Human, X
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dosage Compensation, Genetic

Share to Fragile X Mental Retardation Protein

Share to Nerve Tissue Proteins

Share to Phenotype

Share to Receptors, Androgen

Share to RNA-Binding Proteins

Source

Identifiers

PMID: 11397327
DOI: 10.1097/00125817-200003000-00004

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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