Article
Severe brain atrophy in a case of thalamic variant of sporadic CJD with plaque-like PrP deposition.
Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Jun 2001
Yamashita M, Yamamoto T, Nishinaka K, Udaka F, Kameyama M, Kitamoto T
Abstract excerpt
A 30-year-old woman presented with ataxic gait and progressive mental deterioration, and 3 years later developed myoclonus in the limbs. Subsequently, she lapsed into an akinetic state and died more than 6 years after the onset of disease. The brain weighed 670 g, and preferential degeneration was found in the medial thalamus and the inferior olivary nucleus. In the cerebrum and cerebellum, gliosis and neuronal...
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