Article
Placental bone morphogenetic protein(PLAB) gene expression in normal, pre-malignant and malignant human prostate: Relation to tumor development and progression
1 Jan 2001
Abstract excerpt
The second most common target of prostate-cancer metastasis is bone, and the phenomenon of skeletal metastasis represents the incurable stage of disease. Histologically, skeletal metastasis from prostate cancer is distinctive due to its osteoblastic nature. The osteoblastic bone metastasis shows extensive new bone formation, with possible involvement of the soluble growth factors secreted by tumor cells, such as...
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