Article
Sequence-based typing of HLA class I alleles in Alaskan Yupik Eskimo.
Human immunology - 1 Jun 2001
Ellexson-Turner M E, Leffell M S, Zachary A A, Turner S, Bennett T, Sidebottom D A, Cao K, Fernández-Viña M, Hildebrand W H
Abstract excerpt
In comparison to South America, native North Americans tend to be less diverse in their repertoire of HLA class I alleles. Based upon this observation, we hypothesized that the Yupik Eskimo would exhibit a limited number of previously identified class I HLA alleles. To test this hypothesis, sequence-based typing was performed at the HLA-A, -B and -C loci for 99 Central Yupik individuals from southwestern Alaska....
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