Article
Polymorphic SVA retrotransposons at four loci and their association with classical HLA class I alleles in Japanese, Caucasians and African Americans.
Immunogenetics - 1 Apr 2010
Kulski Jerzy K, Shigenari Atsuko, Inoko Hidetoshi
Abstract excerpt
Polymorphic insertion frequencies of the retrotransposons known as the "SVA" elements were investigated at four loci in the MHC class I genomic region to determine their allele and haplotype frequencies and associations with the HLA-A, -B or -C genes for 100 Japanese, 100 African Americans, 174 Australian Caucasians and 66 reference cell lines obtained from different ethnic groups. The SVA insertions representing...
Topics
- Black or African American
- Alleles
- Asian People
- Genes, MHC Class I
- Genotype
- Humans
- Phylogeny
- Polymorphism, Genetic
- Retroelements
- White People