Article
Evidence that RME-1, a conserved C. elegans EH-domain protein, functions in endocytic recycling.
Nature cell biology - 1 Jun 2001
Grant B, Zhang Y, Paupard M C, Lin S X, Hall D H, Hirsh D
Abstract excerpt
In genetic screens for new endocytosis genes in Caenorhabditis elegans we identified RME-1, a member of a conserved class of Eps15-homology (EH)-domain proteins. Here we show that RME-1 is associated with the periphery of endocytic organelles, which is consistent with a direct role in endocytic transport. Endocytic defects in rme-1 mutants indicate that the protein is likely to have a function in endocytic...
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