Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis.

Gastroenterology - 1 Jun 2001

Laurent-Puig P, Legoix P, Bluteau O, Belghiti J, Franco D, Binot F, Monges G, Thomas G, Bioulac-Sage P, Zucman-Rossi J

Abstract excerpt

BACKGROUND & AIMS: To evaluate how characterization of genetic alterations can help in the elucidation of liver carcinogenesis pathways, 137 tumors were analyzed. METHODS: High-density allelotype, p53, Axin1, and beta-catenin gene mutations were determined. Alterations were analyzed according to clinical parameters. RESULTS: Tumors could be divided into 2 groups according to chromosome stability status. In the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axin Protein
Share to beta Catenin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular

Share to Cytoskeletal Proteins

Share to Genes, p53

Share to Liver Neoplasms

Share to Loss of Heterozygosity

Share to Trans-Activators

Source

Identifiers

PMID: 11375957
DOI: 10.1053/gast.2001.24798

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis.PMID 11375957Read ↗

Genetics of hepatocellular carcinoma.Semantic proximity Read ↗

Genetic Alterations and Oncogenic Pathways in Hepatocellular CarcinomaSemantic proximity Read ↗

Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer.Semantic proximity Read ↗

Genetic profile of hepatocellular carcinoma revealed by array-based comparative genomic hybridization: identification of genetic indicators to predict patient outcome.Semantic proximity Read ↗

Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade – results of an explorative CGH meta-analysisSemantic proximity Read ↗

Clinicopathologic significance of genetic alterations in hepatocellular carcinoma.Semantic proximity Read ↗

Molecular Pathways and Related Target Therapies in Liver CarcinomaSemantic proximity Read ↗

Genetics of hepatobiliary carcinogenesis.Semantic proximity Read ↗

Gene networks and transcriptional regulators associated with liver cancer development and progressionSemantic proximity Read ↗

Comprehensive allelotype study of hepatocellular carcinoma: potential differences in pathways to hepatocellular carcinoma between hepatitis B virus-positive and -negative tumors.Semantic proximity Read ↗

Oncogenetic tree modeling of human hepatocarcinogenesisSemantic proximity Read ↗

Frequent genomic imbalances suggest commonly altered tumour genes in human hepatocarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.