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Article

Probing the 121-136 domain of lecithin:cholesterol acyltransferase using antibodies.

Archives of biochemistry and biophysics - 15 Jan 2001

Murray K R, Nair M P, Ayyobi A F, Hill J S, Pritchard P H, Lacko A G

Abstract excerpt

Lecithin:cholesterol acyltransferase (LCAT) catalyzes the esterification of plasma lipoprotein cholesterol in mammals as part of the reverse cholesterol transport pathway. Studies of the natural mutations of LCAT revealed a region that is highly sensitive to mutations (residues 121-136) and it is highly conserved in six animal species. The purpose of these studies was to investigate the reactivity of wild type...

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Source

Identifiers

PMID: 11368007
DOI: 10.1006/abbi.2000.2154

Genes

LCAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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