Article
Structure and function of lecithin cholesterol acyl transferase: new insights from structural predictions and animal models.
Current opinion in lipidology - 1 Apr 2000
Peelman F, Vandekerckhove J, Rosseneu M
Abstract excerpt
The enzyme lecithin cholesterol acyl transferase is responsible for the synthesis of most of the cholesteryl esters in plasma, and therefore plays a key role in lipoprotein metabolism. The relationship between the structure and function of lecithin cholesterol acyl transferase has been extensively studied in the past years, and new data appeared in 1999 documenting the substrate specificity and physiological role...
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