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Severe combined immunodeficiency mouse-human skin chimeras: a unique animal model for the study of psoriasis and cutaneous inflammation

1 May 2001

Abstract excerpt

Elucidation of the molecular and cellular mechanisms responsible for the pathogenesis of psoriasis had been significantly handicapped due to lack of an ideal animal model. To overcome this hurdle several investigators have developed a number of animal models for psoriasis. Recent establishment of the SCID-human skin chimeras with transplanted psoriasis plaques has opened new vistas to study the molecular...

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Share to Cytokine Signaling Pathways and Interactions
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PMID: 11359377
DOI: 10.1046/j.1365-2133.2001.04178.x

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