Article
[Psoriasis SCID-mouse model].
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - 1 Jul 2006
Pfeffer J, Kaufmann R, Boehncke W-H
Abstract excerpt
Psoriasis is characterized by a complex phenotype and pathogenesis along with polygenic determination. Several psoriasis animal models have only been able to incompletely reproduce the disease. A xenogeneic transplantation approach, grafting skin from psoriatic patients onto mice with a severe combined immunodeficiency (SCID), was the first to meet the criteria for a psoriasis model. During the last 10 years,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.