Article
Apolipoprotein-E phenotype and basal activity of low-density lipoprotein receptor are independent of changes in plasma lipoprotein subfractions after cholesterol ingestion in Japanese subjects.
Nutrition (Burbank, Los Angeles County, Calif.) - 1 Apr 2001
Homma Y, Kobayashi T, Yamaguchi H, Ozawa H, Homma K, Ishiwata K
Abstract excerpt
We investigated whether the apolipoprotein-E (apoE) phenotype and the basal activity of low-density lipoprotein (LDL) receptor, which were reported to be the major determinants for increase in plasma LDL levels by cholesterol ingestion, have the same role in Japanese subjects whose diet is low in fat and cholesterol. Cholesterol (750 mg/d) was added to the ordinary diet as a dried egg-yolk supplement for 4 wk to...
Topics
- Apolipoproteins E
- Apoproteins
- Basal Metabolism
- Cholesterol
- Cholesterol, Dietary
- Female
- Humans
- Hyperlipoproteinemias
- Immunoblotting
- Japan
- Lipids
- Lipoproteins
- Male
- Middle Aged