Article
Imperfect units of an extended microsatellite structure involving single nucleotide changes.
Electrophoresis - 1 Apr 2001
Wang W, Bittles A H
Abstract excerpt
Short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) are widely used as markers in human genome studies. We have characterized a highly polymorphic STR locus (D20S85) with (AAAG)n repeats, by a combination of direct DNA sequencing and single-strand conformation polymorphism (SSCP) analysis. Eight STR alleles were first identified on denaturing gels, and SSCP gels were then used to demonstrate...
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