Article
Proliferation, cell cycle and apoptosis in cancer.
Nature - 17 May 2001
Evan G I, Vousden K H
Abstract excerpt
Beneath the complexity and idiopathy of every cancer lies a limited number of 'mission critical' events that have propelled the tumour cell and its progeny into uncontrolled expansion and invasion. One of these is deregulated cell proliferation, which, together with the obligate compensatory suppression of apoptosis needed to support it, provides a minimal 'platform' necessary to support further neoplastic...
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