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Article

Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation

1 Jan 2001

Abstract excerpt

High-dose chemotherapy and peripheral blood stem cell transplantation (PBSCT) may accelerate telomere length loss in haematopoietic stem cells. As data including pre-and post-treatment samples are lacking, we studied leukocyte telomere length and telomerase activity before and after treatment in breast cancer patients randomized to receive 5 adjuvant courses FEC (5-FU, epirubicin and cyclophosphamide) (n = 17),...

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PMID: 11355946
DOI: 10.1054/bjoc.2001.1803

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