Article
Influence of adjuvant hormone therapy and chemotherapy on the immune system analysed in the bone marrow of patients with breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2003
Solomayer Erich-Franz, Feuerer Markus, Bai Lianhua, Umansky Victor, Beckhove Philipp, Meyberg Gabriele C, Bastert Gunther, Schirrmacher Volker, Diel Ingo Jakob
Abstract excerpt
PURPOSE: Bone marrow is a special compartment for antitumor immunological memory in patients with breastcancer. Until now, the influence of adjuvant systemic therapy on the immune system has only been investigated in peripheral blood and not in bone marrow. In this study, we analyzed the effect of hormone therapy and chemotherapy on the immune activation status in bone marrow. EXPERIMENTAL DESIGN: In 34 patients...
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