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Article

Teicoplanin stress-selected mutations increasing sigma(B) activity in Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Jun 2001

Bischoff M, Berger-Bächi B

Abstract excerpt

A natural rsbU mutant of Staphylococcus aureus, unable to activate the alternative transcription factor sigma(B) via the RsbU pathway and therefore forming unpigmented colonies, produced first-step teicoplanin-resistant mutants upon selection for growth in the presence of teicoplanin, of which the majority were of an intense orange color. By using an asp23 promoter-luciferase fusion as an indicator, the pigmented...

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Identifiers

PMID: 11353616
DOI: 10.1128/AAC.45.6.1714-1720.2001
PMCID: PMC90536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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