Article
Phenotype determination of anti-GM3 positive cells in atherosclerotic lesions of the human aorta. Hypothetical role of ganglioside GM3 in foam cell formation.
Biochimica et biophysica acta - 14 Feb 2001
Bobryshev Y V, Lord R S, Golovanova N K, Gracheva E V, Zvezdina N D, Prokazova N V
Abstract excerpt
Earlier we reported that atherosclerotic plaques contain cells which were specifically and very intensively stained with anti-GM3 antibodies although no GM3 positive cells were detected in the normal non-diseased arterial intima. Because of their lipid inclusions, GM3 positive cells in atherosclerotic lesions seemed to be foam cells but their origin needed clarification. Using an immunohistochemical technique in...
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