Article
Genetic evaluation of peroxisomal and cytosolic acetoacetyl-CoA thiolase isozymes in n-alkane-assimilating diploid yeast, Candida tropicalis.
Cell biochemistry and biophysics - 1 Jan 2000
Ueda M, Kanayama N, Tanaka A
Abstract excerpt
The n-alkane-assimilating diploid yeast, Candida tropicalis, possesses two acetoacetyl-CoA thiolase (Thiolase I) isozymes encoded by one allele: peroxisomal and cytosolic Thiolase Is encoded by both CT-T1A and CT-T1B. To clarify the function of peroxisomal and cytosolic Thiolase Is, the site-directed mutation leading Thiolase I delta C6 without a putative C-terminal peroxisomal targeting signal was introduced on...
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