Article
Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder.
The American journal of psychiatry - 1 May 2001
Nurnberger J I, Foroud T, Flury L, Su J, Meyer E T, Hu K, Crowe R, Edenberg H, Goate A, Bierut L, Reich T, Schuckit M, Reich W
Abstract excerpt
OBJECTIVE: Depression (major depression or depressive syndrome) is more prevalent in alcoholic than in nonalcoholic subjects in families with multiple members with alcoholism studied as part of the Collaborative Study on the Genetics of Alcoholism (National Institute on Alcohol Abuse and Alcoholism). First-degree relatives of probands with comorbid alcoholism and depression have a higher prevalence of both...
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