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Article

Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis.

Oncogene - 1 Mar 2001

Fulda S, Meyer E, Friesen C, Susin S A, Kroemer G, Debatin K M

Abstract excerpt

Apoptosis in response to cellular stress such as treatment with cytotoxic drugs is mediated by effector caspases (caspase-3) which can be activated by different initiator pathways. Here, we report on a cell type specific triggering of death receptor and/or mitochondrial pathways upon drug treatment. In type I cells (BJAB), both the receptor and the mitochondrial pathway were activated upon drug treatment, since...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11314043
DOI: 10.1038/sj.onc.1204141

Genes

FADD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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