Article
The optimal measure of allelic association.
Proceedings of the National Academy of Sciences of the United States of America - 24 Apr 2001
Morton N E, Zhang W, Taillon-Miller P, Ennis S, Kwok P Y, Collins A
Abstract excerpt
Allelic association between pairs of loci is derived in terms of the association probability rho as a function of recombination theta, effective population size N, linear systematic pressure v, and time t, predicting both rho(rt), the decrease of association from founders and rho(ct), the increase by genetic drift, with rho(t) = rho(rt) + rho(ct). These results conform to the Malecot equation, with time replaced...
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