Expression ofpls, a Gene Closely Associated with themecAGene of Methicillin-ResistantStaphylococcus aureus, Prevents Bacterial Adhesion In Vitro

Abstract excerpt

The pls gene, coding for a large surface protein of methicillin-resistant Staphylococcus aureus, was cloned from a strain which adheres poorly to several mammalian proteins. The structure of pls revealed three distinct repeat regions, one of which was a serine-aspartate repeat characteristic of the Clf-Sdr family of surface proteins in staphylococci. The lengths of the repeat regions varied in different clinical...

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