Article
Metabolism of glucocorticoids and mineralocorticoids in patients with adrenal incidentalomas.
European journal of clinical investigation - 1 Dec 2000
Maser-Gluth C, Reincke M, Allolio B, Schulze E
Abstract excerpt
BACKGROUND: Adrenal incidentalomas are mostly nonfunctioning adrenocortical adenomas (NFI). However, in 5%-12% of the patients a preclinical Cushing's syndrome (PCS) with autonomous cortisol production by the tumour is present. Since urinary free cortisol excretion is not sensitive enough to determine subclinical hypercortisolism, in the present study more sensitive indicators of daily cortisol production were...
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