Article
Effects of genetic background on thermoregulation and fatty acid-induced uncoupling of mitochondria in UCP1-deficient mice.
The Journal of biological chemistry - 13 Apr 2001
Hofmann W E, Liu X, Bearden C M, Harper M E, Kozak L P
Abstract excerpt
An interaction between free fatty acids and UCP1 (uncoupling protein-1) leading to de-energization of mitochondria was assumed to be a key event for triggering heat production in brown fat. Recently, Matthias et al., finding indistinguishable de-energization of isolated brown fat mitochondria by...
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