Article
Chemical modification patterns of active and inactive as well as procapsid-bound and unbound DNA-packaging RNAof bacterial virus Phi29.
Virology - 15 Mar 2001
Zhang C, Trottier M, Chen C, Guo P
Abstract excerpt
During replication, the lengthy genome of dsDNA viruses is translocated with remarkable velocity into the limited space within the preformed procapsid. We previously found that a viral-encoded RNA (pRNA) played a key role in bacterial virus phi29 DNA translocation. Design of mutant pRNA sets containing two and three inactive mutant pRNAs, respectively, led to the conclusion that the stoichiometry of pRNA in DNA...
Topics
- Bacillus Phages
- Capsid
- DNA Replication
- DNA, Viral
- Models, Molecular
- Mutation
- Nucleic Acid Conformation
- Phylogeny
- Protein Precursors
- RNA, Viral
- Transcription, Genetic
- Virus Assembly