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<i>In vitro</i> fertilisation of mouse oocytes reconstructed by transfer of metaphase II chromosomes results in live births

1 Feb 2001

Abstract excerpt

The interaction between nucleus and cytoplasm can be explored through nuclear transfer. We describe here another tool to investigate this interaction: MII meiotic apparatus transfer (MAT) between mouse oocytes. In this study, the MII oocyte meiotic apparatus or spindle from C57BL/6 mice, a black strain, was transferred into an enucleated metaphase oocyte from Kunming mouse, a white strain. The results showed that...

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PMID: 11273037
DOI: 10.1017/s0967199401001022

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