Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9.

Journal of virology - 1 Apr 2001

Ahn J H, Xu Y, Jang W J, Matunis M J, Hayward G S

Abstract excerpt

The human cytomegalovirus (HCMV) major immediate-early protein IE2 is a nuclear phosphoprotein that is believed to be a key regulator in both lytic and latent infections. Using yeast two-hybrid screening, small ubiquitin-like modifiers (SUMO-1, SUMO-2, and SUMO-3) and a SUMO-conjugating enzyme (U...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus
Share to Immediate-Early Proteins
Share to Ligases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Small Ubiquitin-Related Modifier Proteins

Share to SUMO-1 Protein

Share to Ubiquitin-Conjugating Enzyme UBC9

Share to Ubiquitin-Conjugating Enzymes

Share to Ubiquitins

Source

Open in PubMed Open full text

Identifiers

PMID: 11264375
DOI: 10.1128/JVI.75.8.3859-3872.2001
PMCID: PMC114877

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11264375-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9.PMID 11264375Read ↗

Proteasome-Independent Disruption of PML Oncogenic Domains (PODs), but Not Covalent Modification by SUMO-1, Is Required for Human Cytomegalovirus Immediate-Early Protein IE1 To Inhibit PML-Mediated Transcriptional RepressionSemantic proximity Read ↗

The Human Cytomegalovirus DNA Polymerase Processivity Factor UL44 Is Modified by SUMO in a DNA-Dependent MannerSemantic proximity Read ↗

Phosphorylation by CK2 increases the SUMO-dependent activity of Cytomegalovirus transactivator IE2Semantic proximity Read ↗

SUMOylation of the human cytomegalovirus 72-kilodalton IE1 protein facilitates expression of the 86-kilodalton IE2 protein and promotes viral replication.Semantic proximity Read ↗

The ND10 Component Promyelocytic Leukemia Protein Acts as an E3 Ligase for SUMOylation of the Major Immediate Early Protein IE1 of Human Cytomegalovirus.Semantic proximity Read ↗

Functional interaction of the human cytomegalovirus IE2 protein with histone deacetylase 2 in infected human fibroblastsSemantic proximity Read ↗

Ability of the Human Cytomegalovirus IE1 Protein To Modulate Sumoylation of PML Correlates with Its Functional Activities in Transcriptional Regulation and Infectivity in Cultured Fibroblast CellsSemantic proximity Read ↗

Characterization of a human cytomegalovirus with phosphorylation site mutations in the immediate-early 2 protein.Semantic proximity Read ↗

The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cellsSemantic proximity Read ↗

Human Cytomegalovirus Protein pp71 Induces Daxx SUMOylationSemantic proximity Read ↗

Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays.Semantic proximity Read ↗

The Human Cytomegalovirus IE1 Protein Antagonizes PML Nuclear Body-Mediated Intrinsic Immunity via the Inhibition of PML De Novo SUMOylation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.