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Article

Identification of a recurrent BRCA1 mutation in German breast-cancer and/or ovarian-cancer families.

Journal of cancer research and clinical oncology - 1 Jan 2001

Hofmann W, Jandrig B, Classen E, Nestle-Kraemling C, Chang-Claude J, Scherneck S

Abstract excerpt

Specific BRCA1 mutations have been reported to be common within particular populations. We have investigated German breast- and/or ovarian-cancer families and detected a recurrent carboxy-terminal BRCA1 mutation, 5622C > T, using PCR-based restriction assay and haplotype analysis. Unrelated families carrying this BRCA1 mutation shared two different disease-associated haplotypes, indicating two independent...

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Source

Identifiers

PMID: 11260866
DOI: 10.1007/s004320000204

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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